This screenplay is an original Deadpool crossover adventure blending Deadpool, X-Men, Spider-Man, and Venom universes. It’s structured as a darkly comedic action movie with heavy Symbiote horror elements, POV sequences, dream scenes, and fourth-wall jokes.
The Symbiote plague breaks out and the government mistakenly labels Deadpool as Patient Zero, sending the city into panic. Meanwhile, actual Symbiotes begin infecting civilians, growing stronger, and hunting mutants for hosts.
As Wade tries to go about his day, things rapidly get worse. A failed experiment in a university lab releases spores during a thunderstorm, and civilians begin turning violent as early-stage hosts struggle against the Symbiotes overtaking their bodies. Reports of “violent deranged citizens” increase, and mass panic erupts throughout the city.
Deadpool gets into several chaotic escapes— down a tunnel, through parks, chased by dogs, police, and random groups of people who now blame him for everything. Meanwhile, the Symbiote invasion quietly escalates as more hosts mutate and die in the street, foreshadowing the coming war.
By the end of Act I:
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